The SCORE (Systematic Coronary Risk Evaluation) chart estimates 10-year risk of cardiovascular mortality. Statin therapy is generally recommended for primary prevention when the 10-year risk of a fatal cardiovascular event is:
- A ≥ 5% (high risk) ✓
- B ≥ 10% (very high risk)
- C ≥ 1% in all adults regardless of risk factors
- D ≥ 15% (extreme risk only)
Correct answer: A. ≥ 5% (high risk)
Explanation
According to ESC/EAS 2019 guidelines, patients with ≥ 5% 10-year risk of fatal cardiovascular disease on SCORE (corresponding to 'high risk') are candidates for statin therapy for primary prevention, particularly if LDL-C remains elevated after lifestyle modification. SCORE ≥ 10% denotes 'very high risk'. India's national guidelines (based on WHO/ISH CVD risk charts) recommend risk stratification for all adults above 40 years to guide preventive pharmacotherapy.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
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Written and medically reviewed by the StethoPrep medical team.