A 55-year-old woman is diagnosed with FIGO Stage IA ovarian mucinous cystadenocarcinoma. Which statement about ovarian mucinous tumors is CORRECT?

• A They are bilateral in over 60% of malignant cases
• B CA-125 is the most reliable serum marker for monitoring
• C Pseudomyxoma peritonei from ovarian origin is the most common cause of mucinous ascites
• D They are usually unilateral and can grow very large ✓

Explanation

Ovarian mucinous tumors are usually unilateral and can attain enormous size (up to 30 cm). Bilaterality suggests a primary gastrointestinal metastasis. CEA is more useful than CA-125 for mucinous tumors. Pseudomyxoma peritonei most commonly arises from appendiceal mucinous neoplasms, not ovarian primaries.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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