A 45-year-old woman is diagnosed with FIGO Stage IC epithelial ovarian cancer (serous type) after total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. Which of the following is the STANDARD adjuvant treatment?

• A Platinum-based chemotherapy (carboplatin + paclitaxel) ✓
• B Whole abdominal radiotherapy
• C Hormonal therapy with tamoxifen
• D Observation only; surgery is curative at Stage IC

Explanation

For Stage IC epithelial ovarian cancer, adjuvant chemotherapy with carboplatin and paclitaxel (6 cycles) is the standard of care as it significantly reduces recurrence risk. Stage IC includes tumors limited to one or both ovaries with capsule rupture, tumor on ovarian surface, or malignant cells in peritoneal washings. Whole abdominal radiotherapy has largely been abandoned due to toxicity with inferior outcomes compared to platinum-based regimens.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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