A 62-year-old postmenopausal woman presents with a solid right ovarian mass (12 cm). Histopathology shows transitional (urothelial-like) nests of cells in a fibrous stroma. The tumor is benign and found incidentally. Which ovarian tumor does this describe?
- A Granulosa cell tumour
- B Brenner tumour (benign) ✓
- C Endometrioid carcinoma
- D Transitional cell carcinoma of the ovary
Correct answer: B. Brenner tumour (benign)
Explanation
Benign Brenner tumours are composed of nests of transitional (urothelial-like) epithelial cells embedded in abundant fibrous stroma. They are usually small, unilateral, and found incidentally. They are part of the surface epithelial-stromal tumor group. True transitional cell carcinoma of the ovary is rare and malignant; it lacks the benign nested architecture in fibrous stroma.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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