A histopathology report on an ovarian tumour from a 19-year-old girl describes a reticular pattern of primitive cells lining spaces, with a central vessel projecting into a space lined by tumour cells. Which structure has been described?
- A Schiller-Duval body ✓
- B Call-Exner body
- C Henderson-Paterson body
- D Psammoma body
Correct answer: A. Schiller-Duval body
Explanation
The Schiller-Duval body, a central capillary surrounded by tumour cells within a space resembling a glomerulus, is the pathognomonic feature of the yolk sac (endodermal sinus) tumour. These tumours secrete alpha-fetoprotein and occur mainly in girls and young women. Call-Exner bodies belong to granulosa cell tumours, Henderson-Paterson bodies to molluscum contagiosum, and psammoma bodies to serous papillary lesions.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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