A 42-year-old woman has bilateral solid ovarian enlargement discovered during evaluation for early satiety. Both ovaries are enlarged but retain their shape. Biopsy shows ovarian stroma infiltrated by signet-ring cells containing intracytoplasmic mucin. The most common primary site of this tumour is:
- A Colon
- B Stomach ✓
- C Appendix
- D Breast
Correct answer: B. Stomach
Explanation
Krukenberg tumour is defined as ovarian metastasis containing mucin-filled signet-ring cells, classically from a gastric primary. The stomach remains the most common origin in standard textbook teaching and in Indian exam convention, though colorectal primaries are increasingly reported in Western series. Bilateral involvement with preservation of ovarian shape is typical. Breast and colon can metastasise to ovary, but those deposits usually lack the diffuse signet-ring pattern that defines Krukenberg tumour.
Reference: Shaw's Textbook of Gynecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.