A 60-year-old woman has bilateral ovarian masses with signet-ring cells on biopsy. Endoscopy reveals linitis plastica of the stomach. What is the most likely diagnosis for the ovarian masses?
- A Brenner tumor
- B Krukenberg tumor ✓
- C Mucinous cystadenocarcinoma
- D Serous cystadenocarcinoma
Correct answer: B. Krukenberg tumor
Explanation
Krukenberg tumor is a metastatic adenocarcinoma to the ovary, most commonly from a gastric primary, especially the diffuse or linitis plastica type. It characteristically shows signet-ring cells and is typically bilateral. Brenner tumors are primary transitional cell tumors of the ovary. Primary mucinous and serous cystadenocarcinomas would not explain the gastric linitis plastica.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.