Which ovarian tumor is most commonly associated with Peutz-Jeghers syndrome?
- A Mucinous cystadenoma
- B Dysgerminoma
- C Sertoli-Leydig cell tumor
- D Sex cord tumor with annular tubules ✓
Correct answer: D. Sex cord tumor with annular tubules
Explanation
Sex cord tumor with annular tubules is strongly associated with Peutz-Jeghers syndrome, especially when bilateral and small. In this syndrome, these tumors tend to be benign or low-grade. Mucinous tumors are linked to pseudomyxoma peritonei, dysgerminoma to gonadoblastoma in dysgenetic gonads, and Sertoli-Leydig cell tumors occur sporadically with androgenic manifestations.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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