A histopathology report from an oophorectomy specimen describes a unilocular cyst filled with greasy sebaceous material and hair, with a solid mural nodule containing cartilage and thyroid-like tissue. Which is the MOST common benign ovarian neoplasm?

• A Serous cystadenoma
• B Mature cystic teratoma (dermoid cyst) ✓
• C Mucinous cystadenoma
• D Ovarian fibroma

Explanation

The description is classic for a mature cystic teratoma, which is the single most common benign ovarian neoplasm and is composed of well differentiated derivatives of all three germ layers, typically skin with sebaceous glands and hair, plus cartilage, bone or thyroid tissue. Serous cystadenoma is the most common benign epithelial tumour but lacks sebaceous content and hair, which excludes option A.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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