A 30-year-old woman with a Stage IA dysgerminoma of the right ovary undergoes fertility-sparing surgery. Which adjuvant therapy is most appropriate?
- A Bleomycin, etoposide, cisplatin (BEP)
- B Observation only ✓
- C Carboplatin single agent
- D Whole abdominal radiotherapy
Correct answer: B. Observation only
Explanation
Stage IA dysgerminoma is confined to one ovary with an intact capsule and no surface involvement. Cure rates with surgery alone exceed 95 percent, so observation is standard. BEP chemotherapy is reserved for higher stages or recurrence. Dysgerminoma is exquisitely radiosensitive, but radiation is avoided to preserve fertility. Carboplatin is not used for stage IA.
Reference: Berek and Hacker's Gynecologic Oncology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.