Obstetrics & Gynaecology · Ovarian Tumors (Benign, Malignant, Classification)

Which ovarian tumor is characterized histologically by Schiller-Duval bodies and produces AFP?

  • A Yolk sac tumor
  • B Embryonal carcinoma
  • C Choriocarcinoma
  • D Immature teratoma
Correct answer: A. Yolk sac tumor

Explanation

Schiller-Duval bodies (perivascular formations with a central vessel) are pathognomonic for yolk sac tumor (endodermal sinus tumor), which characteristically produces AFP. Choriocarcinoma produces beta-hCG. Embryonal carcinoma has solid sheets of pleomorphic cells without Schiller-Duval bodies. Immature teratoma contains immature neuroectoderm.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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