A 40-year-old woman with a pelvic mass has markedly elevated serum inhibin A and B. Which ovarian tumor is most likely?
- A Dysgerminoma
- B Yolk sac tumor
- C Granulosa cell tumor ✓
- D Endometrioid carcinoma
Correct answer: C. Granulosa cell tumor
Explanation
Granulosa cell tumors are sex cord-stromal tumors that characteristically secrete inhibin A and C, which are useful for diagnosis and monitoring recurrence. Dysgerminoma produces LDH. Yolk sac tumor produces AFP. Endometrioid carcinoma is an epithelial tumor and does not secrete inhibin.
Reference: Berek and Hacker's Gynecologic Oncology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.