Meigs syndrome classically consists of which triad?

• A Ovarian dermoid cyst, ascites, and bilateral pleural effusions
• B Ovarian thecoma, elevated CA-125, and pleural effusion
• C Granulosa cell tumour, ascites, and endometrial hyperplasia
• D Ovarian fibroma, ascites, and right-sided pleural effusion ✓

Explanation

Meigs syndrome is the triad of benign ovarian fibroma (or fibrothecoma), ascites, and right-sided pleural effusion, all of which resolve after surgical removal of the ovarian tumour. The pleural effusion is typically right-sided due to trans-diaphragmatic lymphatic flow. CA-125 can be mildly elevated, mimicking malignancy. Granulosa cell tumours cause endometrial hyperplasia but are not part of Meigs syndrome.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

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