Meigs' syndrome consists of which classic triad?

• A Ovarian cystadenocarcinoma, ascites, and bilateral pleural effusions
• B Ovarian fibroma, ascites, and right-sided pleural effusion ✓
• C Ovarian teratoma, hydrothorax, and anemia
• D Krukenberg tumor, massive ascites, and left pleural effusion

Explanation

Meigs' syndrome classically comprises: (1) ovarian fibroma (or thecoma, granulosa cell tumor — benign solid ovarian tumor), (2) ascites, and (3) right-sided pleural effusion, all of which resolve completely after removal of the ovarian tumor. The pleural fluid is typically a transudate entering via diaphragmatic lymphatics, predominantly right-sided. Pseudo-Meigs' syndrome refers to the same triad occurring with other tumors (teratoma, struma ovarii, ovarian metastases). CA-125 may be elevated, mimicking malignancy.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

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