Which ovarian tumor is associated with pseudo-Meigs syndrome and elevated CA-125, and is derived from ovarian surface epithelium with benign histology?
- A Serous cystadenoma
- B Brenner tumor
- C Fibroma ✓
- D Thecoma
Correct answer: C. Fibroma
Explanation
Ovarian fibroma is classically associated with Meigs syndrome (ovarian tumor + ascites + pleural effusion). Pseudo-Meigs syndrome occurs when an ovarian fibroma is associated with elevated CA-125 along with ascites and pleural effusion, mimicking malignancy. The tumor itself is benign and derived from ovarian stroma. CA-125 normalizes after tumor removal.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.