Sertoli-Leydig cell tumour (arrhenoblastoma) of the ovary most commonly belongs to which WHO classification category?
- A Surface epithelial-stromal tumour
- B Germ cell tumour
- C Sex cord-stromal tumour ✓
- D Metastatic tumour to the ovary
Correct answer: C. Sex cord-stromal tumour
Explanation
Sertoli-Leydig cell tumours (arrhenoblastomas) are classified under sex cord-stromal tumours of the ovary. They produce androgens causing virilisation (amenorrhoea, clitoromegaly, hirsutism). They are typically unilateral and low-grade malignant. The tumour marker INHIBIN B can be elevated. Surface epithelial tumours include serous/mucinous cystadenomas; germ cell tumours include dysgerminoma and teratoma.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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