Which ovarian germ cell tumour is characterised by the presence of Schiller-Duval bodies on histology and is associated with elevated serum AFP?

• A Dysgerminoma
• B Immature teratoma
• C Yolk sac tumour (endodermal sinus tumour) ✓
• D Choriocarcinoma

Explanation

Yolk sac tumour (endodermal sinus tumour) is characterised histologically by Schiller-Duval bodies — perivascular structures resembling the endodermal sinuses of the rat placenta — and produces AFP, which serves as a tumour marker for monitoring. Dysgerminoma produces LDH and is equivalent to testicular seminoma. Choriocarcinoma produces beta-hCG. Immature teratoma contains embryonic neural tissue and may produce AFP but lacks Schiller-Duval bodies.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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