A woman with suspected pre-eclampsia at 30 weeks has an sFlt-1/PlGF ratio of 20. According to current evidence, this result is most useful to:
- A Rule out pre-eclampsia within 1 week ✓
- B Rule in pre-eclampsia
- C Predict fetal growth restriction
- D Indicate immediate delivery
Correct answer: A. Rule out pre-eclampsia within 1 week
Explanation
An sFlt-1/PlGF ratio below 38 has a negative predictive value exceeding 99% for ruling out pre-eclampsia within 1 week, allowing safe outpatient management. It is not a rule-in test and does not by itself mandate delivery.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.