Obstetrics & Gynaecology · Hypertensive Disorders in Pregnancy (Pre-eclampsia, Eclampsia)

A 32-year-old woman with chronic hypertension conceives. At 22 weeks gestation, she develops proteinuria >300 mg/24 hours, which was absent at booking. Her blood pressure has risen from a baseline of 138/90 to 162/108 mmHg. What is the MOST appropriate diagnosis?

  • A Chronic hypertension
  • B Gestational hypertension
  • C Superimposed pre-eclampsia
  • D De novo pre-eclampsia
Correct answer: C. Superimposed pre-eclampsia

Explanation

Superimposed pre-eclampsia is diagnosed in a woman with pre-existing chronic hypertension who develops new-onset proteinuria after 20 weeks, or a sudden significant rise in BP in a woman whose hypertension was previously well-controlled. This patient had controlled chronic hypertension and now demonstrates a worsening BP along with new proteinuria, satisfying the criteria. The onset before 34 weeks also portends a more severe course.

Reference: Williams Obstetrics, 26th ed.

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