Under current ACOG and ISSHP diagnostic criteria for pre-eclampsia, which of the following features has been REMOVED from the formal diagnostic requirements compared with older classifications?
- A Thrombocytopenia
- B Generalised oedema ✓
- C Impaired liver function
- D Pulmonary oedema
Explanation
Oedema was dropped from the diagnostic criteria because it occurs in up to 60 percent of normal pregnancies and lacks specificity for pre-eclampsia. Current criteria require new-onset hypertension after 20 weeks with either proteinuria or, in its absence, any of the following severe features: thrombocytopenia below 100,000 per microlitre, serum creatinine above 1.1 mg/dL, transaminase elevation to twice normal, pulmonary oedema, or new-onset headache or visual symptoms. The other three options are all retained end-organ criteria supporting diagnosis without proteinuria.
Reference: Williams Obstetrics, 26th ed.
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