Obstetrics & Gynaecology · Hypertensive Disorders in Pregnancy (Pre-eclampsia, Eclampsia)

A primigravida at 31 weeks presents with right upper quadrant pain. Investigations show platelet count 72,000/microL, AST 180 U/L, ALT 210 U/L, and LDH 650 U/L. Using the Mississippi classification for HELLP syndrome, this patient is classified as:

  • A Mississippi Class II
  • B Mississippi Class I
  • C Mississippi Class III
  • D Partial HELLP syndrome
Correct answer: A. Mississippi Class II

Explanation

The Mississippi classification grades complete HELLP syndrome by the nadir platelet count: Class I is platelets 50,000/microL or less, Class II is platelets greater than 50,000 but up to 100,000/microL, and Class III is platelets greater than 100,000 but up to 150,000/microL. B count of 72,000/microL therefore places her in Class II. Partial HELLP requires incomplete fulfilment of the triad, whereas this patient has thrombocytopenia, elevated transaminases, and elevated LDH, satisfying all three components of complete HELLP.

Reference: Fernando Arias' Practical Guide to High-Risk Pregnancy and Delivery, 5th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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