Obstetrics & Gynaecology · Hypertensive Disorders in Pregnancy (Pre-eclampsia, Eclampsia)

According to the Pritchard regimen, which is used commonly in Indian practice for eclampsia, the total intramuscular loading dose of magnesium sulfate is:

  • A 4 g intravenously plus 10 g intramuscularly, 5 g in each buttock
  • B 6 g intravenously over 20 minutes, no intramuscular component
  • C 10 g intramuscularly alone, divided into two buttocks
  • D 2 g intravenously every hour until seizures stop
Correct answer: A. 4 g intravenously plus 10 g intramuscularly, 5 g in each buttock

Explanation

The Pritchard regimen gives a 4 g intravenous loading dose over 5 to 10 minutes together with 10 g intramuscularly, 5 g into each buttock, a total loading dose of 14 g. Maintenance is 5 g intramuscularly every 4 hours alternating buttocks, continued for 24 hours after the last seizure or delivery. The 6 g intravenous loading dose belongs to the Zuspan regimen. Option D describes an unstructured infusion rather than a recognised regimen.

Reference: Fernando Arias' Practical Guide to High-Risk Pregnancy and Delivery, 5th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

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