Obstetrics & Gynaecology · Hypertensive Disorders in Pregnancy (Pre-eclampsia, Eclampsia)

Which of the following features qualifies a hypertensive pregnant woman for the diagnosis of pre-eclampsia with severe features according to current ACOG criteria, even without severe hypertension (≥160/110)?

  • A Proteinuria >500 mg in 24 hours
  • B A single episode of serum creatinine 0.9 mg/dL
  • C Fundal height greater than expected for gestational age
  • D New-onset thrombocytopenia with platelet count <100,000/μL
Correct answer: D. New-onset thrombocytopenia with platelet count <100,000/μL

Explanation

ACOG criteria for severe features of pre-eclampsia include new-onset thrombocytopenia (platelets <100,000/μL), renal insufficiency (creatinine >1.1 mg/dL), impaired liver function (LFTs twice normal), pulmonary oedema, new-onset headache unresponsive to analgesia, and visual symptoms. Proteinuria quantity is no longer a criterion for severity; platelet count <100,000 qualifies regardless of BP level.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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