A 32-year-old primigravida with severe pre-eclampsia at 30 weeks is started on IV labetalol. Which antihypertensive is CONTRAINDICATED in pregnancy when used as oral maintenance therapy beyond 20 weeks?
- A Atenolol ✓
- B Methyldopa
- C Nifedipine
- D Labetalol
Correct answer: A. Atenolol
Explanation
Atenolol is a pure beta-1 selective blocker associated with fetal growth restriction, low birth weight, and neonatal bradycardia when used throughout pregnancy; it is therefore contraindicated beyond the first trimester. Methyldopa remains the most extensively studied and preferred oral agent; labetalol and nifedipine (SR) are acceptable alternatives.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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