A 28-year-old primigravida at 26 weeks develops HELLP syndrome. Her platelet count is 62,000/µL, LDH 1,100 U/L, AST 180 U/L. She is hemodynamically stable with no fetal compromise. According to Mississippi classification of HELLP, she belongs to which class?
- A Class 2 (platelets 50,000–100,000/µL) ✓
- B Class 1 (platelets <50,000/µL)
- C Class 3 (platelets 100,000–150,000/µL)
- D Partial HELLP — does not classify
Correct answer: A. Class 2 (platelets 50,000–100,000/µL)
Explanation
The Mississippi classification of HELLP syndrome is based on platelet nadir: Class 1 is platelets ≤50,000/µL, Class 2 is platelets 50,001–100,000/µL, and Class 3 is platelets 100,001–150,000/µL (also termed partial HELLP or ELLP without full hemolysis). With platelets of 62,000/µL, she falls in Class 2. Class 1 carries the highest maternal morbidity including placental abruption and acute renal failure.
Reference: Williams Obstetrics, 26th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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