Obstetrics & Gynaecology · Hypertensive Disorders in Pregnancy (Pre-eclampsia, Eclampsia)

In the HYPITAT trial, induction of labour at 37 weeks in women with gestational hypertension or mild pre-eclampsia compared to expectant management resulted in:

  • A No difference in adverse maternal outcomes
  • B Significant reduction in adverse maternal outcomes but doubled caesarean rate
  • C Worse neonatal outcomes in the induction group
  • D Significant reduction in adverse maternal outcomes without increasing caesarean rate
Correct answer: D. Significant reduction in adverse maternal outcomes without increasing caesarean rate

Explanation

The HYPITAT trial (Netherlands, 2009) randomised women with gestational hypertension or mild pre-eclampsia at 36–41 weeks to induction vs expectant management. Induction significantly reduced adverse maternal outcomes (progression to severe disease, HELLP, eclampsia) without a significant increase in caesarean section rate. Neonatal outcomes were comparable between groups.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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