In the HYPITAT trial, induction of labour at 37 weeks in women with gestational hypertension or mild pre-eclampsia compared to expectant management resulted in:
- A No difference in adverse maternal outcomes
- B Significant reduction in adverse maternal outcomes but doubled caesarean rate
- C Worse neonatal outcomes in the induction group
- D Significant reduction in adverse maternal outcomes without increasing caesarean rate ✓
Correct answer: D. Significant reduction in adverse maternal outcomes without increasing caesarean rate
Explanation
The HYPITAT trial (Netherlands, 2009) randomised women with gestational hypertension or mild pre-eclampsia at 36–41 weeks to induction vs expectant management. Induction significantly reduced adverse maternal outcomes (progression to severe disease, HELLP, eclampsia) without a significant increase in caesarean section rate. Neonatal outcomes were comparable between groups.
Reference: Williams Obstetrics, 26th ed.
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