Leishmaniasis and Tropical/Geographic Dermatoses MCQs

Dermatology · 12 free questions with answers & explanations.

1. Cutaneous leishmaniasis (CL) in India is predominantly caused by Leishmania tropica. The classic Old World CL lesion is called 'Oriental sore'. Which clinical feature is the HALLMARK of this presentation?
2. Post-kala-azar dermal leishmaniasis (PKDL) most commonly follows treatment of visceral leishmaniasis (kala-azar) caused by Leishmania donovani. The characteristic skin manifestation of PKDL in India is:
3. Chromoblastomycosis is a tropical subcutaneous mycosis. The pathognomonic tissue finding on KOH/biopsy is:
4. A 35-year-old man from Bihar presents with a chronic painless nodulo-ulcerative lesion on the face that began 2 years ago as a papule. Smear from the ulcer edge shows Leishman-Donovan bodies within macrophages. The lesion is on the nose and has partially destroyed the nasal cartilage. Which species and clinical form does this represent?
5. The Leishmanin (Montenegro) skin test is used to assess cellular immunity in leishmaniasis. In which clinical form of the disease does this test give a NEGATIVE result despite active infection?
6. First-line treatment for cutaneous leishmaniasis in India according to current guidelines is:
7. A soldier returning from deployment in Afghanistan develops a slowly enlarging, painless, ulcerating nodule on the forearm with raised indurated edges and a granular base. He has been in the endemic area for 6 months. Slit-skin smear and culture confirms Leishmania tropica. The first-line systemic treatment for cutaneous leishmaniasis in India is:
8. A 38-year-old man presents with hypopigmented macules and nodules on the face, a destructive nasopharyngeal ulceration with palate perforation, and hoarseness. He is from the Amazon region of Brazil. Leishmania braziliensis is confirmed. This form of leishmaniasis is termed:
9. Post-kala-azar dermal leishmaniasis (PKDL) typically occurs after treatment of visceral leishmaniasis. Which of the following best describes the timeline and morphology of Indian PKDL (caused by L. donovani)?
10. Post-kala-azar dermal leishmaniasis (PKDL) in India is caused by which species and typically appears after treatment of visceral leishmaniasis by what time interval?
11. A 35-year-old man returning from the Amazon presents with a destructive lesion involving the nasal septum and oral mucosa, with a 'tapir nose' deformity. Skin smear shows kinetoplast-bearing amastigotes. The causative agent and the treatment of choice are:
12. Cutaneous larva migrans (creeping eruption) is caused by the larvae of which organism, and what is the treatment of choice?