Dermatology · Leishmaniasis and Tropical/Geographic Dermatoses

First-line treatment for cutaneous leishmaniasis in India according to current guidelines is:

  • A Intralesional sodium stibogluconate
  • B Oral miltefosine for 28 days
  • C Topical paromomycin ointment
  • D Intravenous amphotericin B
Correct answer: A. Intralesional sodium stibogluconate

Explanation

For localised cutaneous leishmaniasis, intralesional sodium stibogluconate (SSG) is the first-line treatment, given weekly until healing. Oral miltefosine is reserved for extensive or treatment-resistant cases. IV amphotericin B (liposomal) is used for visceral leishmaniasis (kala-azar), not for simple cutaneous disease. Topical paromomycin is used in some geographical settings but is not first-line in India.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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