Post-kala-azar dermal leishmaniasis (PKDL) most commonly follows treatment of visceral leishmaniasis (kala-azar) caused by Leishmania donovani. The characteristic skin manifestation of PKDL in India is:
- A Hypopigmented macules and papules on the face, trunk and extremities ✓
- B Diffuse hyperpigmentation with ichthyosis
- C Extensive scarring alopecia
- D Erythematous nodules resembling lepromatous leprosy
Correct answer: A. Hypopigmented macules and papules on the face, trunk and extremities
Explanation
PKDL in India typically presents as hypopigmented macules and papules, progressing to nodules and plaques, appearing months to years after successful treatment of visceral leishmaniasis. The lesions are concentrated on the face (especially malar areas), trunk and extremities. PKDL is important epidemiologically as patients serve as reservoirs for transmission. The African form (Sudan) differs—it may occur during or immediately after VL treatment with nodular morphology. Diagnosis requires demonstration of parasites in skin lesions.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.