Under NTEP, a patient diagnosed with MDR-TB is found to have additional resistance to levofloxacin but remains susceptible to bedaquiline and linezolid. This pattern is classified as:
- A Pre-XDR-TB ✓
- B XDR-TB
- C MDR-TB with extended resistance
- D TDR-TB
Correct answer: A. Pre-XDR-TB
Explanation
Pre-XDR-TB is defined as MDR-TB with additional resistance to any fluoroquinolone (levofloxacin or moxifloxacin). XDR-TB requires additional resistance to a fluoroquinolone plus at least one Group A drug (bedaquiline or linezolid). Since this patient remains susceptible to bedaquiline and linezolid, it is pre-XDR-TB, not XDR-TB.
Reference: Guidelines on Programmatic Management of Drug-Resistant TB in India, 2021 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.