Under NTEP, the continuation phase of the standard regimen for new drug-sensitive TB (DS-TB) patients is:
- A 4HRE (isoniazid, rifampicin, ethambutol for 4 months)
- B 4HR (isoniazid and rifampicin for 4 months) ✓
- C 6HE (isoniazid and ethambutol for 6 months)
- D 5HRZ (isoniazid, rifampicin, pyrazinamide for 5 months)
Explanation
Under NTEP (rebranded from RNTCP in 2020), all new DS-TB patients receive 2HRZE (intensive phase) followed by 4HR (continuation phase), replacing the older 4HRE continuation phase. The omission of ethambutol from the continuation phase was based on WHO 2010 revised guidelines. Previously treated DS-TB patients confirmed by DST to be drug-sensitive also receive this same 6-month regimen.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
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Written and medically reviewed by the StethoPrep medical team.