Under the National AIDS Control Programme (NACP), which of the following is the recommended first-line antiretroviral therapy (ART) regimen for adults and adolescents living with HIV?

• A Zidovudine + Lamivudine + Nevirapine
• B Abacavir + Lamivudine + Lopinavir/ritonavir
• C Stavudine + Lamivudine + Efavirenz
• D Tenofovir + Lamivudine + Dolutegravir (TLD) ✓

Explanation

Under NACP Phase V, the recommended first-line ART regimen is TLD: Tenofovir (300 mg) + Lamivudine (300 mg) + Dolutegravir (50 mg). This is a single daily tablet with high efficacy and better tolerability. Option A was used in earlier phases. Option C (stavudine-based) was phased out due to toxicity. Option B is a second-line regimen.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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