Under the National Vector Borne Disease Control Programme (NVBDCP), the drug of choice for radical cure of Plasmodium vivax malaria to eliminate hypnozoites is:
- A Primaquine 0.25 mg/kg/day for 14 days ✓
- B Chloroquine 25 mg/kg over 3 days
- C Artesunate 4 mg/kg/day for 3 days
- D Doxycycline 100 mg twice daily for 7 days
Correct answer: A. Primaquine 0.25 mg/kg/day for 14 days
Explanation
Primaquine 0.25 mg/kg/day for 14 days is used for radical cure of P. vivax malaria to eliminate dormant hypnozoites in the liver and prevent relapse. Chloroquine treats the erythrocytic stage but does not address hypnozoites. Artesunate is used for P. falciparum. G6PD status must be checked before administering primaquine as it can cause haemolysis.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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