India's National Vector Borne Disease Control Programme (NVBDCP) currently recommends Artemisinin-based Combination Therapy (ACT) as the first-line treatment for uncomplicated Plasmodium falciparum malaria. The recommended regimen is:

• A Artesunate + Amodiaquine for 3 days
• B Artemether-Lumefantrine for 3 days
• C Chloroquine for 3 days + Primaquine single dose
• D Artesunate + Sulfadoxine-Pyrimethamine ✓

Explanation

NVBDCP guidelines recommend Artesunate + Sulfadoxine-Pyrimethamine (AS+SP) as the first-line ACT for uncomplicated P. falciparum malaria in India. Primaquine (0.75 mg/kg single dose) is added on Day 2 as a gametocytocidal agent. WHO globally recommends multiple ACT options, but India's national programme specifies AS+SP as the standard first-line ACT.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.