Under NTEP, which regimen is used for treatment of drug-susceptible TB in adults (NEW SHORTER REGIMEN introduced after 2022)?

• A 4-month regimen: 2HRZE/2HR
• B BPaLM (Bedaquiline, Pretomanid, Linezolid, Moxifloxacin) for 6 months
• C 2HRZE/4HRE (with ethambutol throughout)
• D 2HRZE/4HR — 6 months standard regimen ✓

Explanation

For new drug-susceptible TB patients in India under NTEP, the standard 6-month regimen 2HRZE/4HR (2 months intensive phase with isoniazid, rifampicin, pyrazinamide, ethambutol; followed by 4 months continuation phase with isoniazid and rifampicin) remains the standard of care. BPaLM is the WHO-recommended regimen for drug-resistant TB (XDR/pre-XDR). The TB-PRACTECAL and ZeNix trials informed newer DR-TB regimens.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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