Ulipristal acetate used for emergency contraception is correctly described as:
- A A selective progesterone receptor modulator given as a single 30 mg dose within 120 hours of unprotected intercourse ✓
- B An antiprogestin given as 600 mg followed by misoprostol after 48 hours
- C A combined oestrogen-progestogen regimen repeated twice, 12 hours apart
- D A pure anti-oestrogen given daily for 5 days
Correct answer: A. A selective progesterone receptor modulator given as a single 30 mg dose within 120 hours of unprotected intercourse
Explanation
Ulipristal acetate is a selective progesterone receptor modulator; a single 30 mg oral dose taken within 120 hours (5 days) delays or inhibits ovulation and is more effective than levonorgestrel in the 72 to 120 hour window. Option B describes medical abortion with mifepristone, a different drug and indication. Option C is the Yuzpe regimen, and ulipristal is not an anti-oestrogen, killing D.
Reference: Katzung's Basic and Clinical Pharmacology, 16th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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