Cu-T 380A (copper-T IUD) prevents pregnancy primarily by which of the following mechanisms?

• A Inhibition of ovulation through systemic hormonal effect
• B Thickening of cervical mucus to prevent sperm penetration only
• C Spermicidal effect of copper ions and creation of hostile intrauterine environment ✓
• D Blocking fertilization by creating a physical barrier at the fallopian tube

Explanation

Cu-T 380A works primarily through the spermicidal effect of copper ions (Cu²⁺), which impair sperm motility, acrosomal reaction, and fertilizing capacity. Additionally, copper creates a sterile inflammatory reaction in the endometrium, altering the uterine environment to prevent implantation. It does not inhibit ovulation. With a failure rate of <1%, it is one of the most effective long-acting reversible contraceptives (LARCs).

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.