Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

An investigator finds that countries with higher average chocolate consumption win more Nobel Prizes and concludes that eating chocolate makes individuals more likely to win. What is this erroneous inference called?

  • A Overmatching
  • B Simpson's paradox
  • C Regression dilution bias
  • D Ecological fallacy
Correct answer: D. Ecological fallacy

Explanation

An ecological study compares group-level aggregates, and a correlation observed between groups need not hold at the individual level. Applying the group-level association to individuals is the ecological fallacy. Simpson's paradox describes reversal of an association after stratification by a confounder, regression dilution refers to attenuation of associations from measurement error in exposure, and overmatching occurs in matched designs when matching on a variable linked to exposure but not disease reduces the observable association.

Reference: Park's Textbook of Preventive and Social Medicine, 26th ed.

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