Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

In a case-control study on cervical cancer, 60 of 100 cases and 30 of 100 controls were exposed to HPV. The Odds Ratio is:

  • A 2.0
  • B 3.0
  • C 3.5
  • D 6.0
Correct answer: C. 3.5

Explanation

In the 2×2 table: a=60 (exposed cases), b=40 (unexposed cases), c=30 (exposed controls), d=70 (unexposed controls). OR = (a×d)/(b×c) = (60×70)/(40×30) = 4200/1200 = 3.5. The odds ratio approximates relative risk when disease prevalence is low, and here indicates that HPV-exposed women have 3.5 times the odds of developing cervical cancer compared to unexposed women.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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