Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

Herd immunity threshold (HIT) for a disease with basic reproduction number (R₀) of 5 is:

  • A 60%
  • B 75%
  • C 80%
  • D 90%
Correct answer: C. 80%

Explanation

Herd immunity threshold = 1 − (1/R₀) = 1 − (1/5) = 1 − 0.2 = 0.8 = 80%. This is the proportion of the population that must be immune (through vaccination or prior infection) to interrupt sustained transmission. For measles (R₀ ≈ 12–18), HIT is 92–95%. For COVID-19 wild-type (R₀ ≈ 2–3), HIT was approximately 50–67%.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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