Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

In a study comparing two treatments for hypertension, the investigators did not know which treatment each patient received. This design element is called:

  • A Randomization
  • B Matching
  • C Stratification
  • D Blinding
Correct answer: D. Blinding

Explanation

Blinding (masking) prevents knowledge of treatment allocation from influencing assessment or behavior. If investigators are unaware of treatment assignment, it is single-blind; if both participants and investigators are unaware, it is double-blind. Blinding minimizes performance bias and detection bias. Randomization ensures comparable groups at baseline but is distinct from blinding.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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