Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

Bradford Hill's criteria are used to assess causal inference in epidemiology. Which criterion states that the exposure must precede the outcome in time?

  • A Consistency
  • B Temporality
  • C Plausibility
  • D Coherence
Correct answer: B. Temporality

Explanation

Temporality — that the cause must precede the effect — is the only sine qua non (essential) criterion in Bradford Hill's guidelines for causation; without it, a causal relationship is impossible. Consistency refers to replication of findings across different studies and populations. Plausibility requires a biologically credible mechanism. Coherence requires the causal interpretation to be consistent with the natural history and biology of the disease.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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