Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

The Bradford Hill criterion 'consistency' in establishing causality means:

  • A A dose-response relationship exists between exposure and outcome
  • B The association is specific to one disease and one exposure
  • C The association has been observed repeatedly in different populations, places, and times
  • D Removal of the exposure leads to reduction in disease incidence
Correct answer: C. The association has been observed repeatedly in different populations, places, and times

Explanation

Consistency (one of Bradford Hill's 9 criteria) refers to the repeated observation of the same association across different populations, settings, methodologies, and time periods. Dose-response (biological gradient) is a separate criterion. Specificity refers to the association being limited to one exposure-disease pair. Reversibility (cessation of exposure reducing risk) is related to but separate from the criterion of temporality.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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