Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

A prospective cohort study enrolls healthy individuals and finds that among 500 smokers followed for 10 years, 80 developed lung cancer, while among 500 non-smokers, 10 developed lung cancer. Calculate the attributable risk percent (attributable fraction) among exposed:

  • A 62.5%
  • B 87.5%
  • C 75.0%
  • D 93.0%
Correct answer: B. 87.5%

Explanation

Incidence in smokers = 80/500 = 0.16; incidence in non-smokers = 10/500 = 0.02. Attributable risk = 0.16 − 0.02 = 0.14. Attributable risk percent (ARP) = (AR/incidence in exposed) × 100 = (0.14/0.16) × 100 = 87.5%. This means 87.5% of lung cancer in smokers is attributable to smoking.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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