Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

Which of the following Bradford Hill criteria is the ONLY one that, if present, is considered SUFFICIENT on its own to infer causality?

  • A Strength of association
  • B Specificity
  • C Experiment (reversibility)
  • D Coherence
Correct answer: C. Experiment (reversibility)

Explanation

The experiment criterion (also called reversibility) — demonstrating that removing the cause reduces or eliminates the effect — is considered the strongest evidence for causality among Bradford Hill's criteria and the only one that, if demonstrated by a properly controlled experiment, is sufficient on its own to establish causality. No single observational criterion is individually sufficient; strength of association, specificity, and coherence all support but do not alone confirm causation.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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