In a matched case-control study, 10 pairs are concordant for exposure, 20 pairs have only the case exposed, and 8 pairs have only the control exposed. What is the matched odds ratio?
- A 1.25
- B 2.50 ✓
- C 2.00
- D 3.50
Correct answer: B. 2.50
Explanation
In a matched case-control study, the Mantel-Haenszel matched OR = discordant pairs with case exposed / discordant pairs with control exposed = 20/8 = 2.5. Concordant pairs (where both or neither are exposed) do not contribute to the OR estimate. Options A, B, and D arise from incorrect application of the formula.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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