Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

A case-control study finds that 60 of 100 cases and 30 of 100 controls had prior statin use. What is the odds ratio for statin use in relation to the outcome?

  • A 1.5
  • B 3.5
  • C 2.0
  • D 4.0
Correct answer: B. 3.5

Explanation

Odds in cases = 60/40 = 1.5; Odds in controls = 30/70 ≈ 0.4286. OR = 1.5/0.4286 = 3.5. An OR > 1 indicates higher odds of exposure among cases compared to controls. This is distinct from relative risk, which cannot be directly computed from a case-control design without incidence data.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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