Community Medicine (PSM) · Epidemiology (Study Designs, Bias, Systematic Review, Measures of Association)

Berkson's bias is characteristically associated with which study design?

  • A Community-based cohort study
  • B Randomized controlled trial
  • C Hospital-based case-control study
  • D Ecological study
Correct answer: C. Hospital-based case-control study

Explanation

Berkson's bias (hospital admission bias) occurs when hospital-based case-control studies select cases and controls from admitted patients. Hospitalized individuals differ from the general population, and patients with combinations of diseases are over-represented, creating spurious associations. This is a form of selection bias.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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