A researcher compares blood pressure reduction across four drug groups. The appropriate statistical test for comparing means of a continuous variable across more than two independent groups is:

• A Paired t-test
• B Independent t-test
• C Chi-square test
• D One-way ANOVA ✓

Explanation

One-way ANOVA (Analysis of Variance) is appropriate for comparing means of a continuous variable across more than two independent groups. A paired t-test compares two related samples; an independent t-test compares two independent groups; chi-square test compares categorical data proportions. ANOVA tests whether at least one group mean differs significantly from others.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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