A researcher wants to determine if the mean blood glucose levels differ significantly between diabetics treated with metformin versus diet control alone. With two independent normally distributed groups and equal variances, which statistical test is most appropriate?
- A Paired t-test
- B Unpaired (independent) t-test ✓
- C Chi-square test
- D Mann-Whitney U test
Correct answer: B. Unpaired (independent) t-test
Explanation
The unpaired (independent samples) t-test is used to compare means of two independent groups when data are normally distributed and variances are assumed equal. A paired t-test is used for matched or before-after comparisons in the same subjects. The chi-square test is for categorical data, and the Mann-Whitney U is for non-parametric comparison of two independent groups.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.